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Publications & Presentations

Featured Content

Society for Immunotherapy of Cancer (SITC) Annual Meeting, November 8-10, in Houston, TX
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A phase 1 clinical trial of GEN2, a personalizing immunotherapy gene vector product, in combination with valganciclovir in adult patients with hepatocellular carcinoma or tumors metastatic to liver
Alison L. Hannah
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BIO International Convention, June 3-6, 2024 in San Diego, CA

Personalizing, Off-the-shelf, Systemic, Cancer Immunotheraphy
Robert G Johnson, M.D., Ph.D.
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American Society of Gene & Cell Therapy (ASGCT) Annual Meeting, May 7-11, 2024 in Baltimore, MD

Single-Chain Variable Fragment-Based Cell Surface Marker-Targeting By Sindbis-Pseudotyped Retrovectors
Makoto Sato, Alexander Cunha, Noriyuki Kasahara, Cecilia Roh, and Robert G. Johnson
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An Integrase Deleted Retrovector with Persistent Payload Expression without Integration Suitable for Prophylactic and Therapeutic Applications
Bradford H. Steele, Jacqueline Fischer-Lougheed, Stephanie Lees, Cecilia Roh, and Robert G. Johnson
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American Association for Cancer Research (AACR) Annual Meeting, April 5-10, 2024 in San Diego, CA

Evaluation of scFv and Diabody Pseudotyped Sindbis Engineered Retrovectors for Targeted Cancer Therapy
Makoto Sato, Alexander Cunha, Sara Collins, Noriyuki Kasahara, Cecilia Roh, and Robert G. Johnson
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Serial assessment of GEN2, a Retroviral Vector for Gene Transfer of an Optimized Thymidine Kinase and GM-CSF, for Genomic Integration into Peripheral Blood Mononuclear Cells (PBMCs) in a Phase 1 Trial in Adult Patients with Solid Tumors
Alison L. Hannah, Noriyuki Kasahara, Li Liu, Allen Wang, Joe McNulty, Robert G. Johnson
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BioProcess International (BPI) US West Annual Meeting, March 11-14, 2024 in San Diego, CA

Intensified Enveloped Vector Production From HEK293T Cells in FLEXSAFE® RM Using Perfusion Bioprocessing
Lynn Svay, Christine Urrea, Hu Zhang, Robert G. Johnson
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Debottleneck Process Development for Targeted Preclinical Enveloped Vector Production
Lauren Slowskei, Hu Zhang, Lynn Svay, Robert G. Johnson
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Society for Immunotherapy of Cancer (SITC) 38th Annual Meeting, November 3-5, 2023 in San Diego, CA

Synergistic Effects of Mediated Gene Therapy with GEN2 (HSV-TK) and GEN1018 (IL-12) in an Experimental Model of Colorectal Cancer
Joshua Yang, Cecilia Roh, Jacqueline Fischer-Lougheed, Lauren Slowskei, Hu Zhang, Joseph McNulty, Noriyuki Kasahara, and Robert G. Johnson
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IL-12 Vectors Engineered to Encode a Functional P35-P40 Heterodimer or a Single P35 Subunit for Cancer Immunotheraphy
Cecilia Roh, Jacqueline Fischer-Lougheed, Stephanie Lees, and Robert G. Johnson
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American Society of Gene and Cell Therapy (ASGCT), May 16-20, 2023 in Los Angeles, CA

Non-Replicating, Non-Integrating Vector for Immunotherapy and Vaccine Applications
Jacqueline Fischer-Lougheed, Bradford H. Steele, Stephanie Lees, Cecilia Roh, and Robert G. Johnson
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Intensified Enveloped Vector Production Using Continuous Perfusion Bioprocessing
Lynn Svay, Hu Zhang, Robert G. Johnson
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Optimization of a Suicide Gene Vector for the GEN2 Cancer Immunotherapy Clinical Trial
Cecilia Roh, Joseph McNulty, Jacqueline Fischer-Lougheed, Makoto Sato, and Robert G. Johnson
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